PROCESS FOR MANUFACTURING MACROCYCLIC PEPTIDES

The invention provides a novel process for manufacturing a compound of formula (I), or a salt thereof, wherein PG1, PG2 and PG3 are amino protective groups. The process according to the invention is particularly suitable for large-scale manufacturing under GMP conditions. L'invention concerne u...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	HOFFMANN-EMERY, Fabienne Roxane, LARSSON, Ulf Goeran, ADAM, Jean-Michel, PUENTENER, Kurt, BLISS, Fritz, DOTT, Pascal Jean Claude
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY PEPTIDES
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Beschreibung
Zusammenfassung:	The invention provides a novel process for manufacturing a compound of formula (I), or a salt thereof, wherein PG1, PG2 and PG3 are amino protective groups. The process according to the invention is particularly suitable for large-scale manufacturing under GMP conditions. L'invention concerne un nouveau procédé de fabrication d'un composé de formule (I), ou d'un sel de celui-ci, PG1, PG2 et PG3 étant des groupes protecteurs amino. Le procédé selon l'invention est particulièrement adapté à la fabrication à grande échelle dans des conditions BPF.