INHIBITORS OF MALIC ENZYME 1

The present disclosure relates to compounds that inhibit malic enzyme 1. The disclosure further relates to methods of treating cancers mediated by malic enzyme 1. La présente divulgation concerne des composés qui inhibent l'enzyme malique 1. La divulgation concerne en outre des méthodes de trai...

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Bibliographische Detailangaben
Hauptverfasser:	CANTLEY, Lewis, SHAN, Mengrou, LIN, Lin, KAMIKAWA, Akio, KANEKO, Osamu, LYSSIOTIS, Costas
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	The present disclosure relates to compounds that inhibit malic enzyme 1. The disclosure further relates to methods of treating cancers mediated by malic enzyme 1. La présente divulgation concerne des composés qui inhibent l'enzyme malique 1. La divulgation concerne en outre des méthodes de traitement de cancers médiés par l'enzyme malique 1.