PHARMACEUTICAL COMPOSITIONS AND METHODS OF ADMINISTRATION
The present disclosure describes novel compounds and compositions and methods of making and using thereof related that are capable of inhibiting PAK1 and associated diseases or disorders, including tumors and cancerous cells. The inventive compounds are more efficacious and stable than IPA-3 without...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | SHENOY, Somanath GESELOWITZ, Daniel A CUMMINGS, Brian CRICH, David HOMAN, Harvey D |
| description | The present disclosure describes novel compounds and compositions and methods of making and using thereof related that are capable of inhibiting PAK1 and associated diseases or disorders, including tumors and cancerous cells. The inventive compounds are more efficacious and stable than IPA-3 without needing liposomal formulations as vehicles for the compounds.
La présente invention concerne des composés et compositions nouveaux et leurs procédés de fabrication et d'utilisation associés qui sont capables d'inhiber PAK1 et des maladies ou des troubles associés, y compris des tumeurs et des cellules cancéreuses. Les composés de l'invention sont plus efficaces et stables que l'IPA-3 sans nécessiter de formulations liposomales en tant que véhicules pour les composés. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO2023147478A2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO2023147478A2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO2023147478A23</originalsourceid><addsrcrecordid>eNrjZLAM8HAM8nV0dg0N8XR29FFw9vcN8A_2DPH09wtWcPRzUfB1DfHwdwlW8HdTcHTx9fTzDA4JcgRJ8zCwpiXmFKfyQmluBmU31xBnD93Ugvz41OKCxOTUvNSS-HB_IwMjY0MTcxNzC0cjY-JUAQBWZyoK</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PHARMACEUTICAL COMPOSITIONS AND METHODS OF ADMINISTRATION</title><source>esp@cenet</source><creator>SHENOY, Somanath ; GESELOWITZ, Daniel A ; CUMMINGS, Brian ; CRICH, David ; HOMAN, Harvey D</creator><creatorcontrib>SHENOY, Somanath ; GESELOWITZ, Daniel A ; CUMMINGS, Brian ; CRICH, David ; HOMAN, Harvey D</creatorcontrib><description>The present disclosure describes novel compounds and compositions and methods of making and using thereof related that are capable of inhibiting PAK1 and associated diseases or disorders, including tumors and cancerous cells. The inventive compounds are more efficacious and stable than IPA-3 without needing liposomal formulations as vehicles for the compounds.
La présente invention concerne des composés et compositions nouveaux et leurs procédés de fabrication et d'utilisation associés qui sont capables d'inhiber PAK1 et des maladies ou des troubles associés, y compris des tumeurs et des cellules cancéreuses. Les composés de l'invention sont plus efficaces et stables que l'IPA-3 sans nécessiter de formulations liposomales en tant que véhicules pour les composés.</description><language>eng ; fre</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230803&DB=EPODOC&CC=WO&NR=2023147478A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230803&DB=EPODOC&CC=WO&NR=2023147478A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SHENOY, Somanath</creatorcontrib><creatorcontrib>GESELOWITZ, Daniel A</creatorcontrib><creatorcontrib>CUMMINGS, Brian</creatorcontrib><creatorcontrib>CRICH, David</creatorcontrib><creatorcontrib>HOMAN, Harvey D</creatorcontrib><title>PHARMACEUTICAL COMPOSITIONS AND METHODS OF ADMINISTRATION</title><description>The present disclosure describes novel compounds and compositions and methods of making and using thereof related that are capable of inhibiting PAK1 and associated diseases or disorders, including tumors and cancerous cells. The inventive compounds are more efficacious and stable than IPA-3 without needing liposomal formulations as vehicles for the compounds.
La présente invention concerne des composés et compositions nouveaux et leurs procédés de fabrication et d'utilisation associés qui sont capables d'inhiber PAK1 et des maladies ou des troubles associés, y compris des tumeurs et des cellules cancéreuses. Les composés de l'invention sont plus efficaces et stables que l'IPA-3 sans nécessiter de formulations liposomales en tant que véhicules pour les composés.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAM8HAM8nV0dg0N8XR29FFw9vcN8A_2DPH09wtWcPRzUfB1DfHwdwlW8HdTcHTx9fTzDA4JcgRJ8zCwpiXmFKfyQmluBmU31xBnD93Ugvz41OKCxOTUvNSS-HB_IwMjY0MTcxNzC0cjY-JUAQBWZyoK</recordid><startdate>20230803</startdate><enddate>20230803</enddate><creator>SHENOY, Somanath</creator><creator>GESELOWITZ, Daniel A</creator><creator>CUMMINGS, Brian</creator><creator>CRICH, David</creator><creator>HOMAN, Harvey D</creator><scope>EVB</scope></search><sort><creationdate>20230803</creationdate><title>PHARMACEUTICAL COMPOSITIONS AND METHODS OF ADMINISTRATION</title><author>SHENOY, Somanath ; GESELOWITZ, Daniel A ; CUMMINGS, Brian ; CRICH, David ; HOMAN, Harvey D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2023147478A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2023</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>SHENOY, Somanath</creatorcontrib><creatorcontrib>GESELOWITZ, Daniel A</creatorcontrib><creatorcontrib>CUMMINGS, Brian</creatorcontrib><creatorcontrib>CRICH, David</creatorcontrib><creatorcontrib>HOMAN, Harvey D</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SHENOY, Somanath</au><au>GESELOWITZ, Daniel A</au><au>CUMMINGS, Brian</au><au>CRICH, David</au><au>HOMAN, Harvey D</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PHARMACEUTICAL COMPOSITIONS AND METHODS OF ADMINISTRATION</title><date>2023-08-03</date><risdate>2023</risdate><abstract>The present disclosure describes novel compounds and compositions and methods of making and using thereof related that are capable of inhibiting PAK1 and associated diseases or disorders, including tumors and cancerous cells. The inventive compounds are more efficacious and stable than IPA-3 without needing liposomal formulations as vehicles for the compounds.
La présente invention concerne des composés et compositions nouveaux et leurs procédés de fabrication et d'utilisation associés qui sont capables d'inhiber PAK1 et des maladies ou des troubles associés, y compris des tumeurs et des cellules cancéreuses. Les composés de l'invention sont plus efficaces et stables que l'IPA-3 sans nécessiter de formulations liposomales en tant que véhicules pour les composés.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre |
| recordid | cdi_epo_espacenet_WO2023147478A2 |
| source | esp@cenet |
| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | PHARMACEUTICAL COMPOSITIONS AND METHODS OF ADMINISTRATION |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-21T16%3A56%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=SHENOY,%20Somanath&rft.date=2023-08-03&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EWO2023147478A2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |