COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR

Disclosed are compounds of Formula (I): or a pharmaceutically acceptable salt, a tautomer, a stereoisomer, or a deuterated analog thereof, wherein R2, R3, R4, Y1, Y2, X, and Z are as described in any of the embodiments described in this disclosure; compositions thereof; and uses thereof. L'inve...

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Bibliographische Detailangaben
Hauptverfasser:	GUO, Zuojun, RANK, Steven, ZHANG, Jiazhong, SPEVAK, Wayne, HAN, Xinping, ZHANG, Ying, SHI, Songyuan, ALBERS, Aaron, ZHANG, Dongyu, LY, Cuong, CHOWDHURY, Somenath, VANDER WAL, Mark, KWAK, Seung-Hwa, PHAM, Phuongly
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:	Disclosed are compounds of Formula (I): or a pharmaceutically acceptable salt, a tautomer, a stereoisomer, or a deuterated analog thereof, wherein R2, R3, R4, Y1, Y2, X, and Z are as described in any of the embodiments described in this disclosure; compositions thereof; and uses thereof. L'invention concerne : des composés de formule (I) ou un sel pharmaceutiquement acceptable, un tautomère, un stéréoisomère, ou un analogue deutéré de ceux-ci, où R2, R3, R4, Y1, Y2, X, et Z sont tels que décrits dans l'un quelconque des modes de réalisation décrits dans la présente invention ; des compositions de ceux-ci ; et leurs utilisations.