PROCESS FOR THE PREPARATION OF A STERILE, HOMOGENEOUS SUSPENSION FOR INHALATION BY NEBULIZATION

The invention relates to a simple, rapid, cost effective, timesaving and industrially convenient process for the preparation of a sterile, homogeneous suspension of niclosamide for inhalation by nebulization to treat SARS-CoV-2, the coronavirus that causes COVID-19. Further, the present invention al...

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Bibliographische Detailangaben
Hauptverfasser: YILMAZ, Emine, CELIK SAKIZCI, Devrim, CAN, Fatih
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention relates to a simple, rapid, cost effective, timesaving and industrially convenient process for the preparation of a sterile, homogeneous suspension of niclosamide for inhalation by nebulization to treat SARS-CoV-2, the coronavirus that causes COVID-19. Further, the present invention also relates to a new inhalation composition comprising niclosamide, distilled water, dispersing or suspending agents, buffering agents, isotonic agents and preservatives. L'invention concerne un procédé simple, rapide, économique, qui permet de gagner du temps et convient à la production industrielle pour la préparation d'une suspension homogène et stérile de niclosamide pour inhalation par nébulisation afin de traiter le SARS-CoV-2, le coronavirus qui provoque la COVID-19. En outre, la présente invention concerne également une nouvelle composition à inhaler comprenant du niclosamide, de l'eau distillée, des agents dispersants ou suspensifs, des agents tampons, des agents isotoniques et des conservateurs.