COMBINED USE OF ANTI-TROP-2 ANTIBODY-DRUG CONJUGATE AND OTHER THERAPEUTIC AGENTS

A combination of an anti-TROP-2 antibody-drug conjugate and anti-PD-L1 antibody or other chemotherapeutic drugs such as carboplatin or cisplatin, and an application of the combination in the preparation of drugs for preventing and/or treating tumor diseases, wherein the anti-TROP-2 antibody may be S...

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Bibliographische Detailangaben
Hauptverfasser:	GUO, Qi, PAN, Yang, LIU, Gesha, YIN, Wenguo, WEI, Yujun, WANG, Suxia, GE, Junyou, DIAO, Yina, LU, Lian, JIN, Xiaoping
Format:	Patent
Sprache:	chi ; eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A combination of an anti-TROP-2 antibody-drug conjugate and anti-PD-L1 antibody or other chemotherapeutic drugs such as carboplatin or cisplatin, and an application of the combination in the preparation of drugs for preventing and/or treating tumor diseases, wherein the anti-TROP-2 antibody may be Sacituzumab. L'invention concerne une combinaison d'un conjugué anticorps anti-TROP-2-médicament et d'un anticorps anti-PD-L1 ou d'autres médicaments chimiothérapeutiques tels que le carboplatine ou le cisplatine, et une application de ladite combinaison dans la préparation de médicaments destinés à la prévention et/ou au traitement de maladies tumorales, l'anticorps anti-TROP-2 pouvant être le sacituzumab. 抗TROP-2抗体偶联药物与抗PD-L1抗体或其它化疗药物如卡铂或顺铂等的组合，在制备预防和/或治疗肿瘤疾病药物中的应用，其中抗TROP-2抗体可以是Sacituzumab。