METHODS OF TREATING INFLAMMATORY DISEASES WITH COMBINATION OF TL1A INHIBITORS AND IL23 INHIBITORS

Described herein are methods of treating inflammatory diseases or conditions such as inflammatory bowel diseases including Crohn's disease and ulcerative colitis, the methods comprising administering a TL1A inhibitor and an IL23 inhibitor contemporaneously for the duration of treatment or conte...

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Hauptverfasser: MUNOZ, Ernesto J, BARNETT, Burton, LLEWELLYN, Heather
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Described herein are methods of treating inflammatory diseases or conditions such as inflammatory bowel diseases including Crohn's disease and ulcerative colitis, the methods comprising administering a TL1A inhibitor and an IL23 inhibitor contemporaneously for the duration of treatment or contemporaneously during an induction phase of treatment followed by maintenance of response with the TL1A inhibitor alone or IL23 inhibitor alone. L'invention concerne des méthodes de traitement de maladies ou d'états inflammatoires tels que des maladies intestinales inflammatoires comprenant la maladie de Crohn et la colite ulcéreuse, les méthodes comprenant l'administration d'un inhibiteur de TL1A et d'un inhibiteur d'IL 23 simultanément pendant la durée de traitement ou simultanément pendant une phase d'induction de traitement suivie d'une maintenance de réponse avec l'inhibiteur de TL1A seul ou l'inhibiteur d'IL 23 seul.