NOVEL ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE OF SAME

Provided is an artificial nucleic acid having a unit derived from a compound represented by formula (1) or a salt thereof (in the formula, Base represents an aromatic heterocyclic ring group which may have a substituent, or an aromatic hydrocarbon ring group which may have a substituent; X1 represents a hydrogen atom, an alkyl group which may have a substituent, an alkenyl group which may have a substituent, an alkynyl group which may have a substituent, a cycloalkyl group which may have a substituent, or an aryl group which may have a substituent; X2 represents a hydrogen atom or -OR7; R1, R2 and R7 are the same as or different from one another and each independently represent a hydrogen atom, an alkyl group which may have a substituent, an alkenyl group which may have a substituent, an alkynyl group which may have a substituent, a cycloalkyl group which may have a substituent, a cycloalkenyl group which may have a substituent, an aryl group which may have a substituent, a protecting group for a hydroxy group, a phosphino group having a substituent, a dihydroxyphosphinyl group which may have a substituent, or a hydroxymercaptophosphinyl group which may have a substituent; R3, R4, R5 and R6 are the same as or different from one another and each independently represent a hydrogen atom, an alkyl group which may have a substituent, an alkenyl group which may have a substituent, an alkynyl group which may have a substituent, a cycloalkyl group which may have a substituent, or an aryl group which may have a substituent; Z1 represents O or NZ11; Z11 represents a hydrogen atom, an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, an aryl group, an aralkyl group, or a protecting group for an amino group; Z2 represents a single bond or CZ21Z22; and Z21 and Z22 are the same as or different from each other and each independently represent a hydrogen atom, an alkyl group which may have a substituent, an alkenyl group which may have a substituent, an alkynyl group which may have a substituent, a cycloalkyl group which may have a substituent, or an aryl group which may have a substituent). La présente invention concerne un acide nucléique artificiel ayant une unité dérivée d'un composé représenté par la formule (1) ou un sel de celui-ci (dans la formule, Base représente un groupe cyclique hétérocyclique aromatique qui peut avoir un substituant, ou un groupe cyclique hydrocarboné aromatique qui peut avoir un substituant ; X1 représente un atome d'hydro