NERVE GRAFTS CONTAINING REGENERATIVE COMPOUNDS, METHODS OF MAKING THE SAME, AND METHODS OF TREATMENT USING THE SAME

A method of preparing a nerve graft includes submerging a nerve graft in a solution including FK506 and a solvent to promote incorporation of FK506 into the nerve graft. A tissue graft includes nerve tissue and FK506 incorporated within the nerve tissue. In the tissue graft, the FK506 is free of hyd...

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Bibliographische Detailangaben
Hauptverfasser: SCOPELIANOS, Angelo, TAJDARAN, Kasra
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:A method of preparing a nerve graft includes submerging a nerve graft in a solution including FK506 and a solvent to promote incorporation of FK506 into the nerve graft. A tissue graft includes nerve tissue and FK506 incorporated within the nerve tissue. In the tissue graft, the FK506 is free of hydrogel and not encapsulated. L'invention concerne un procédé de préparation d'un greffon nerveux qui consiste à immerger un greffon nerveux dans une solution comprenant FK506 et un solvant pour favoriser l'incorporation de FK506 dans le greffon nerveux. Un greffon tissulaire comprend un tissu nerveux et du FK506 incorporé dans le tissu nerveux. Dans le greffon tissulaire, le FK506 est exempt d'hydrogel et non encapsulé.