PHTHALAZINE DERIVATIVES AS PYRUVATE KINASE MODULATORS

The invention relates to a compound of formula (I) which is 6-((1H-pyrazol-4-yl)sulfonyl)-2-((1-cyclopropyl-1H-pyrazol-3-yl)methyl)phthalazin-1(2H)- one; or a salt and/or solvate thereof; and to its use in treating or preventing an inflammatory disease, a disease associated with an undesirable immun...

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Bibliographische Detailangaben
Hauptverfasser:	OSCAR, Barba, DAVID, Cousin
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to a compound of formula (I) which is 6-((1H-pyrazol-4-yl)sulfonyl)-2-((1-cyclopropyl-1H-pyrazol-3-yl)methyl)phthalazin-1(2H)- one; or a salt and/or solvate thereof; and to its use in treating or preventing an inflammatory disease, a disease associated with an undesirable immune response, cancer, obesity, a diabetic disease or a blood disorder. L'invention concerne un composé de formule (I) qui est la 6- ((1H-pyrazol-4-yl)sulfonyl)-2-((1-cyclopropyl-1 H-pyrazol-3-yl)méthyl)phtalazin-1(2H)-one ; ou un sel et/ou un solvate de celui-ci ; et son utilisation dans le traitement ou la prévention d'une maladie inflammatoire, d'une maladie associée à une réponse immunitaire indésirable, du cancer, de l'obésité, d'une maladie diabétique ou d'un trouble sanguin.