SEA URCHIN-DERIVED PEPTIDE AND USE THEREOF

The present invention relates to a sea urchin-derived peptide and a use thereof and, more specifically, to a use of the sea urchin-derived peptide for preventing or treating a disease associated with the V1B receptor of echinotocin, which is a peptide derived from sea urchins. The echinotocin accord...

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Bibliographische Detailangaben
Hauptverfasser:	JO, Seon Mi, AN, Hye Suck, JUNG, Seung Hyun, BAEK, Kyung Hwa, LEE, Jei Ha, LEE, Ha Jeong, KIM, Hea Bin
Format:	Patent
Sprache:	eng ; fre ; kor
Schlagworte:	FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Beschreibung
Zusammenfassung:	The present invention relates to a sea urchin-derived peptide and a use thereof and, more specifically, to a use of the sea urchin-derived peptide for preventing or treating a disease associated with the V1B receptor of echinotocin, which is a peptide derived from sea urchins. The echinotocin according to the present invention was found to have an effect of inducing activation of the V1B receptor, which is a type of vasopressin receptors. The VIB receptor, which is a vasopressin receptor, exists in the anterior pituitary gland and the hippocampus CA2 region and is known to increase intracellular calcium concentration and to be involved in a response to stress and sociality. Therefore, the echinotocin according to the present invention can find various applications in the field of preventing, alleviating, or treating V1B receptor-related diseases. La présente invention concerne un peptide dérivé de l'oursin de mer et son utilisation et, plus précisément, l'invention concerne l'utilisation du peptide dérivé de l'oursin de mer pour la prévention ou le traitement d'une maladie associée au récepteur V1B de l'échinotocine, qui est un peptide dérivé des oursins de mer. L'échinotocine selon la présente invention a pour effet d'induire l'activation du récepteur V1B, qui est un type de récepteur de la vasopressine. Le récepteur V1B, qui est un récepteur de la vasopressine, existe dans la glande pituitaire antérieure et la région de l'hippocampe CA2 et est connue pour augmenter la concentration de calcium intracellulaire et pour être impliquée dans la réponse au stress et la socialité. Par conséquent, l'échinotocine selon la présente invention peut trouver diverses applications dans le domaine de la prévention, du soulagement ou du traitement de maladies associées au récepteur V1B. 본 발명은 성게 유래 펩타이드 및 이의 용도에 관한 것으로, 보다 상세하게는 성게 유래 펩타이드인 이카이노토신의 V1B 수용체 관련 질환의 예방 또는 치료 용도에 관한 것이다. 본 발명에 따른 이카이노토신은 바소프레신 수용체의 일종인 V1B 수용체의 활성화를 유도하는 효과가 있음을 확인하였다. 상기 바소프레신 수용체인 V1B 수용체는 뇌하수체 전엽과 해마 CA2 영역에 존재하며, 세포 내 칼슘 농도를 상승시키고 스트레스에 대한 반응 및 사회성에 관여한다고 알려져 있다. 따라서 본 발명에 따른 이카이노토신은 V1B 수용체 관련 질환의 예방, 개선 또는 치료 분야에서 다양하게 활용될 수 있다.