BCMA ANTIBODY AND USE THEREOF

The present invention relates to an antibody against a B-cell maturation antigen (BCMA) and the use thereof. Specifically, disclosed are an antibody specifically binding to BCMA or an antigen-binding fragment thereof, and an encoding nucleic acid, an expression vector and an expression cell thereof,...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	REN, Jinsheng, CAO, Zhuoxiao, TANG, Renhong, YIN, Bowei, YOU, Shumei, FU, Yayuan
Format:	Patent
Sprache:	chi ; eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to an antibody against a B-cell maturation antigen (BCMA) and the use thereof. Specifically, disclosed are an antibody specifically binding to BCMA or an antigen-binding fragment thereof, and an encoding nucleic acid, an expression vector and an expression cell thereof, a preparation method therefor, a pharmaceutical composition thereof, and the use thereof in the preparation of a pharmaceutical composition for treating diseases, for example, for treating tumors. The present invention has important significance for the development of a therapeutic BCMA antibody drug and a detection reagent. La présente invention concerne un anticorps dirigé contre un antigène de maturation des lymphocytes B (BCMA) et son utilisation. En particulier, l'invention concerne un anticorps qui se lie de manière spécifique à BCMA ou un fragment de liaison à l'antigène de celui-ci, et un acide nucléique codant, un vecteur d'expression et une cellule d'expression de celui-ci, son procédé de préparation, un