NANOPARTICLES FOR RELEASE OF NUCLEIC ACIDS

The invention relates to a nanoparticle comprising at least one cationic lipid, at least one neutral lipid, and at least one pH sensitive lipid which differs from said cationic lipid, which can be used as a vector for the transport and release of nucleic acids within cells. L'invention a trait...

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Bibliographische Detailangaben
Hauptverfasser:	AL MOUAZEN, Eyad, JACQUIER, Arnaud, LOLLO, Giovanna, KRYZA, David, BRIANCON, Stéphanie, ANDRETTO, Valentina, COUDERT, Laurent, SCHAEFFER, Laurent, REPELLIN, Mathieu
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The invention relates to a nanoparticle comprising at least one cationic lipid, at least one neutral lipid, and at least one pH sensitive lipid which differs from said cationic lipid, which can be used as a vector for the transport and release of nucleic acids within cells. L'invention a trait à une nanoparticule comprenant au moins un lipide cationique, au moins un lipide neutre, et au moins un lipide sensible au pH, différent dudit lipide cationique, utile comme vecteur pour le transport et la libération d'acides nucléiques à l'intérieur de cellules.