PYRAZOLOTRIAZINE DERIVATIVES USEFUL AS CDK9 INHIBITORS

The present invention relates to novel compounds of formula (I). These compounds are inhibitors of CDK2 and/or CDK9 and are useful in the treatment of a variety of diseases including hyperproliferative diseases, virally induced infectious diseases, and cardiovascular diseases. La présente invention...

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Bibliographische Detailangaben
Hauptverfasser:	KOESTLER, Roland, KONDROTAS, Julie, THORMANN, Michael, TASSEL, Jean, TRAUBE, Nadine
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to novel compounds of formula (I). These compounds are inhibitors of CDK2 and/or CDK9 and are useful in the treatment of a variety of diseases including hyperproliferative diseases, virally induced infectious diseases, and cardiovascular diseases. La présente invention concerne de nouveaux composés de formule (I). Ces composés sont des inhibiteurs de CDK2 et/ou de CDK9 et sont utiles dans le traitement d'une variété de maladies comprenant des maladies hyperprolifératives, des maladies infectieuses provoquées par un virus et des maladies cardiovasculaires.