ADENOSINE DEAMINASE 2 COMPOSITIONS AND METHODS FOR USING SAME

The invention is directed to mutants of adenosine deaminase 2 (ADA2) that have improved catalytic activity relative to wildtype ADA2, as well as compositions comprising the mutants and methods of using the mutants to treat various conditions. L'invention concerne des mutants d'adénosine dé...

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Bibliographische Detailangaben
Hauptverfasser:	COX, John Robert, BLAZECK, John James
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention is directed to mutants of adenosine deaminase 2 (ADA2) that have improved catalytic activity relative to wildtype ADA2, as well as compositions comprising the mutants and methods of using the mutants to treat various conditions. L'invention concerne des mutants d'adénosine désaminase 2 (ADA2) qui présentent une activité catalytique améliorée par rapport à l'ADA2 de type sauvage, ainsi que des compositions comprenant les mutants et des méthodes d'utilisation des mutants pour traiter diverses affections.