PLATELET DERIVATIVE COMPOSITIONS, AND METHODS OF MAKING AND USING SUCH COMPOSITIONS

Provided herein are materials and methods for the preparation of blood products. In some aspects, provided herein are compositions that include populations of platelet derivatives, including freeze-dried platelet derivatives, methods of producing the same, as well as methods of using the same to tre...

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Bibliographische Detailangaben
Hauptverfasser: ISHLER, Braden Carl, LEE, Amber Nicole, MATHEWS, Michael Alexander, JORDA, Rafael, MOSKOWITZ, Keith Andrew, FITZPATRICK, Glen Michael, MONTGOMERY, Joshua Donald, AMOS, Stephen Edward
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Provided herein are materials and methods for the preparation of blood products. In some aspects, provided herein are compositions that include populations of platelet derivatives, including freeze-dried platelet derivatives, methods of producing the same, as well as methods of using the same to treat a subject. Such platelet derivatives have improved properties, as disclosed herein. La présente invention concerne des matériels et des méthodes destinés à la préparation de produits sanguins. Selon certains aspects, la présente invention concerne des compositions qui comprennent des populations de dérivés de plaquettes, y compris des dérivés de plaquettes lyophilisés, leurs méthodes de production, ainsi que des méthodes d'utilisation de celles-ci pour traiter un sujet. De tels dérivés de plaquettes ont des propriétés améliorées, tels que divulgués dans l'invention.