HETEROCYCLIC COMPOUNDS AND USES THEREOF

HETEROCYCLIC COMPOUNDS AND USES THEREOF

The present disclosure relates to compounds of Formula (I): (I), wherein Ring A, R1, R2, R3, and m are described herein. The present disclosure relates to the use of the compounds of Formula (I), and pharmaceutically acceptable salts, hydrates, solvates, prodrugs, stereoisomers, labeled isotopes, or...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DORICH, Stéphane, DURET, Guillaume, BEVERIDGE, Ramsay, CHAGNON, Felix, BURCH, Jason, FADER, Lee, BOILY, Marc-Olivier, ST-ONGE, Miguel
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present disclosure relates to compounds of Formula (I): (I), wherein Ring A, R1, R2, R3, and m are described herein. The present disclosure relates to the use of the compounds of Formula (I), and pharmaceutically acceptable salts, hydrates, solvates, prodrugs, stereoisomers, labeled isotopes, or tautomers thereof, in the treatment of cGAS-related diseases and disorders. La présente invention concerne des composés de Formule (I) : (I), dans laquelle le cycle A, R1, R2, R3 et m sont décrits dans la description. La présente invention concerne l'utilisation des composés de formule (I), et des sels, des hydrates, des solvates, des promédicaments, des stéréo-isomères, des isotopes marqués ou des tautomères de ceux-ci, dans le traitement de maladies et de troubles liés à cGAS.