INHIBITORS OF HIF-2ALPHA AND METHODS OF USE THEREOF

The present disclosure is directed to compounds that are inhibitors of HIF-2α having a structure according to Formula I, and compositions containing those compounds. Methods of using the compounds for the treatment of diseases, disorders, or conditions are also described. La présente invention conce...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	LELETI, Manmohan Reddy, DREW, Samuel Lawrie, EPPLIN, Matthew, PODUNAVAC, Masa, MATA, Guillaume, ROSEN, Brandon Reid, HARDMAN, Clayton, FOURNIER, Jeremy, LIU, Dongdong, LAWSON, Kenneth Victor, YU, Kai, POWERS, Jay Patrick, BEATTY, Joel Worley, GAL, Balint, MAILYAN, Artur Karenovich
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present disclosure is directed to compounds that are inhibitors of HIF-2α having a structure according to Formula I, and compositions containing those compounds. Methods of using the compounds for the treatment of diseases, disorders, or conditions are also described. La présente invention concerne des composés qui sont des inhibiteurs d'HIF-2α ayant une structure selon la formule I, et des compositions contenant ces composés. L'invention concerne également des procédés d'utilisation des composés pour le traitement de maladies, de troubles ou d'états pathologiques.