IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS

The present application discloses compounds having the following formula (I): or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, and R4 are defined in the specification, as well as methods of making and using the compounds disclosed herein for treating or ameliorating an IL-17 mediate...

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Bibliographische Detailangaben
Hauptverfasser:	VALDES, Alexander E, VENABLE, Jennifer D, MCCARVER, Stefan, BEHENNA, Douglas C, HANNA, Luke E, GORDON, Deane, GOLDBERG, Steven D, WU, Dongpei, LOSKOT, Steven A, SHIREMAN, Brock T, MEDUNA, Steven P, XUE, Xiaohua
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present application discloses compounds having the following formula (I): or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, and R4 are defined in the specification, as well as methods of making and using the compounds disclosed herein for treating or ameliorating an IL-17 mediated syndrome, disorder and/or disease. La présente invention concerne des composés ayant la formule suivante (I) : ou des sels pharmaceutiquement acceptables de ceux-ci, R1, R2, R3 et R4 étant tels que définis dans la description, ainsi que des procédés de fabrication et d'utilisation des composés de l'invention pour traiter ou soulager un syndrome, un trouble et/ou une maladie à médiation par IL-17.