ANTI-CANCER VACCINE COMPOSITION COMPRISING PEPTIDES DERIVED FROM TUMOR-ASSOCIATED ANTIGEN, AND ADJUVANT CONSISTING OF LIPOPEPTIDE AND IMMUNOACTIVE SUBSTANCE, AND USE THEREOF

The present invention pertains to: an anti-cancer vaccine composition comprising [peptides derived from a tumor-associated antigen (TAA)] and [an adjuvant consisting of a lipopeptide and an immunoactive substance]; and a use thereof. Specifically, the peptides derived from a tumor-associated antigen...

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Bibliographische Detailangaben
Hauptverfasser:	KO, Eunbyeol, JUNG, Eunjung, AHN, Byung Cheol, KIM, Hye-jung, CHUN, Eunyuong, YUM, Jung Sun, HEO, Yoonki
Format:	Patent
Sprache:	eng ; fre ; kor
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention pertains to: an anti-cancer vaccine composition comprising [peptides derived from a tumor-associated antigen (TAA)] and [an adjuvant consisting of a lipopeptide and an immunoactive substance]; and a use thereof. Specifically, the peptides derived from a tumor-associated antigen specifically bind to a human leucocyte antigen (HLA), a combination of the peptides having the above characteristics is mixed with the adjuvant in an optimal ratio to prepare a vaccine composition, and the vaccine composition is used for preventing or treating cancer. La présente invention concerne : une composition de vaccin anti-cancer comprenant des peptides dérivés d'un antigène associé à une tumeur (TAA) et un adjuvant consistant en un lipopeptide et une substance immunoactive ; et une utilisation de celle-ci. Spécifiquement, les peptides dérivés d'un antigène associé à une tumeur se lient spécifiquement à un antigène leucocytaire humain (HLA), une combinaison des peptides ayant les caractéristiques ci-dessus est mélangée avec l'adjuvant dans un rapport optimal pour préparer une composition de vaccin, et la composition de vaccin est utilisée pour prévenir ou traiter le cancer. 본 발명은 [종양 연관 항원(TAA) 유래 펩타이드] 및 [리포펩타이드와 면역활성물질로 구성된 아쥬번트]를 포함하는 항암 백신 조성물 및 이의 용도에 관한 것으로, 구체적으로, 본 발명의 종양 연관 항원 유래 펩타이드는 인간 백혈구 항원 (human leucocyte antigen: HLA)에 특이적으로 결합하는 펩타이드이고, 상기 특징을 가진 펩타이드 조합을 상기 아쥬번트와 최적의 비율로 혼합하여 백신 조성물을 제조하고, 이를 암의 예방 또는 치료에 사용하는 것이다.