ALTERNATIVE NOVEL MATERIAL TO BOTULINUM NEUROTOXIN AND PREPARATION METHOD THEREFOR

The present invention relates to an alternative novel material to botulinum neurotoxin and a preparation method therefor, and more specifically, the present invention relates to a myricetin acetyl derivative and a preparation method therefor, wherein the myricetin acetyl derivative has significantly...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	JUN, Soo Youn, YOON, Seong Jun, PARK, Ji Sung, KANG, Sang Hyeon, PARK, Seon Ho, KWON, An Sung
Format:	Patent
Sprache:	eng ; fre ; kor
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to an alternative novel material to botulinum neurotoxin and a preparation method therefor, and more specifically, the present invention relates to a myricetin acetyl derivative and a preparation method therefor, wherein the myricetin acetyl derivative has significantly improved substance stability, including in vivo stability, and has the ability to inhibit SNARE complex formation, and as a result, to inhibit acetylcholine secretion. La présente invention concerne une nouvelle substance de remplacement à la neurotoxine botulique et son procédé de préparation, et plus précisément, la présente invention concerne un dérivé d'acétyle de myricétine et son procédé de préparation, le dérivé d'acétyle de myricétine présentant une stabilité de substance considérablement améliorée, notamment une stabilité in vivo, et présentant la capacité d'inhiber la formation de complexe SNARE et, en conséquence, d'inhiber la sécrétion d'acétylcholine. 본 발명은 보툴리눔 신경독소 대체 신규소재 및 이의 제조방법에 관한 것으로, 더욱 상세하게는 체내 안정성을 포함한 물질의 안정성이 획기적으로 개선된, SNARE 복합체 형성을 저해하여 결과적으로 아세틸콜린 분비를 저해할 수 있는 능력을 갖는 미리세틴 아세틸 유도체, 및 이의 제조방법에 관한 것이다.