AN IMPROVED PROCESS FOR THE PREPARATION OF N-ETHYL- α -METHYL-3-(TRIFLUOROMETHYL)PHENETHYLAMINE HYDROCHLORIDE
The present invention relates to an improved process for the preparation of N-ethyl- α -methyl-3-(trifluoromethyl) phenethylamine hydrochloride (1), having purity greater than 99.5% by HPLC using highly pure 3-(trifluoromethyl) aniline hydrochloride (5) as a key starting material. The present invent...
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| creator | PULLAGURLA, Manik Reddy PITTA, Bhaskar Reddy RANGISETTY, Jagadeesh Babu |
| description | The present invention relates to an improved process for the preparation of N-ethyl- α -methyl-3-(trifluoromethyl) phenethylamine hydrochloride (1), having purity greater than 99.5% by HPLC using highly pure 3-(trifluoromethyl) aniline hydrochloride (5) as a key starting material. The present invention provides process for the purification of N-ethyl-α -methyl-3-(trifluoromethyl) phenethylamine hydrochloride (1), which is substantially free of Impurity A and Impurity B.
La présente invention concerne un processus amélioré de préparation de chlorhydrate de N-éthyl-α-méthyl-3-(trifluorométhyl)phénéthylamine (1), ayant une pureté supérieure à 99,5 % par HPLC faisant appel à du chlorhydrate de 3-(trifluorométhyl)aniline (5) à pureté élevée en tant que matériau de départ clé. La présente invention concerne un processus de purification de chlorhydrate de N-éthyl-α-méthyl-3-(trifluorométhyl)phénéthylamine (1), qui est sensiblement exempt d'impuretés A et d'impuretés B (I) |
| format | Patent |
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La présente invention concerne un processus amélioré de préparation de chlorhydrate de N-éthyl-α-méthyl-3-(trifluorométhyl)phénéthylamine (1), ayant une pureté supérieure à 99,5 % par HPLC faisant appel à du chlorhydrate de 3-(trifluorométhyl)aniline (5) à pureté élevée en tant que matériau de départ clé. La présente invention concerne un processus de purification de chlorhydrate de N-éthyl-α-méthyl-3-(trifluorométhyl)phénéthylamine (1), qui est sensiblement exempt d'impuretés A et d'impuretés B (I)</description><language>eng ; fre</language><subject>CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230316&DB=EPODOC&CC=WO&NR=2023037182A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230316&DB=EPODOC&CC=WO&NR=2023037182A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PULLAGURLA, Manik Reddy</creatorcontrib><creatorcontrib>PITTA, Bhaskar Reddy</creatorcontrib><creatorcontrib>RANGISETTY, Jagadeesh Babu</creatorcontrib><title>AN IMPROVED PROCESS FOR THE PREPARATION OF N-ETHYL- α -METHYL-3-(TRIFLUOROMETHYL)PHENETHYLAMINE HYDROCHLORIDE</title><description>The present invention relates to an improved process for the preparation of N-ethyl- α -methyl-3-(trifluoromethyl) phenethylamine hydrochloride (1), having purity greater than 99.5% by HPLC using highly pure 3-(trifluoromethyl) aniline hydrochloride (5) as a key starting material. The present invention provides process for the purification of N-ethyl-α -methyl-3-(trifluoromethyl) phenethylamine hydrochloride (1), which is substantially free of Impurity A and Impurity B.
La présente invention concerne un processus amélioré de préparation de chlorhydrate de N-éthyl-α-méthyl-3-(trifluorométhyl)phénéthylamine (1), ayant une pureté supérieure à 99,5 % par HPLC faisant appel à du chlorhydrate de 3-(trifluorométhyl)aniline (5) à pureté élevée en tant que matériau de départ clé. La présente invention concerne un processus de purification de chlorhydrate de N-éthyl-α-méthyl-3-(trifluorométhyl)phénéthylamine (1), qui est sensiblement exempt d'impuretés A et d'impuretés B (I)</description><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZMhz9FPw9A0I8g9zdVEAUs6uwcEKbv5BCiEerkC-a4BjkGOIp7-fgr-bgp-ua4hHpI-uwrmNCrq-ELaxrkZIkKebT6h_kD9ESDPAw9UPzHL09fRzVfCIdAEa6-HjH-Tp4srDwJqWmFOcyguluRmU3VxDnD10Uwvy41OLCxKTU_NSS-LD_Y0MjIwNjM0NLYwcjYyJUwUA0kg5RA</recordid><startdate>20230316</startdate><enddate>20230316</enddate><creator>PULLAGURLA, Manik Reddy</creator><creator>PITTA, Bhaskar Reddy</creator><creator>RANGISETTY, Jagadeesh Babu</creator><scope>EVB</scope></search><sort><creationdate>20230316</creationdate><title>AN IMPROVED PROCESS FOR THE PREPARATION OF N-ETHYL- α -METHYL-3-(TRIFLUOROMETHYL)PHENETHYLAMINE HYDROCHLORIDE</title><author>PULLAGURLA, Manik Reddy ; PITTA, Bhaskar Reddy ; RANGISETTY, Jagadeesh Babu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2023037182A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2023</creationdate><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><toplevel>online_resources</toplevel><creatorcontrib>PULLAGURLA, Manik Reddy</creatorcontrib><creatorcontrib>PITTA, Bhaskar Reddy</creatorcontrib><creatorcontrib>RANGISETTY, Jagadeesh Babu</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PULLAGURLA, Manik Reddy</au><au>PITTA, Bhaskar Reddy</au><au>RANGISETTY, Jagadeesh Babu</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>AN IMPROVED PROCESS FOR THE PREPARATION OF N-ETHYL- α -METHYL-3-(TRIFLUOROMETHYL)PHENETHYLAMINE HYDROCHLORIDE</title><date>2023-03-16</date><risdate>2023</risdate><abstract>The present invention relates to an improved process for the preparation of N-ethyl- α -methyl-3-(trifluoromethyl) phenethylamine hydrochloride (1), having purity greater than 99.5% by HPLC using highly pure 3-(trifluoromethyl) aniline hydrochloride (5) as a key starting material. The present invention provides process for the purification of N-ethyl-α -methyl-3-(trifluoromethyl) phenethylamine hydrochloride (1), which is substantially free of Impurity A and Impurity B.
La présente invention concerne un processus amélioré de préparation de chlorhydrate de N-éthyl-α-méthyl-3-(trifluorométhyl)phénéthylamine (1), ayant une pureté supérieure à 99,5 % par HPLC faisant appel à du chlorhydrate de 3-(trifluorométhyl)aniline (5) à pureté élevée en tant que matériau de départ clé. La présente invention concerne un processus de purification de chlorhydrate de N-éthyl-α-méthyl-3-(trifluorométhyl)phénéthylamine (1), qui est sensiblement exempt d'impuretés A et d'impuretés B (I)</abstract><oa>free_for_read</oa></addata></record> |
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| title | AN IMPROVED PROCESS FOR THE PREPARATION OF N-ETHYL- α -METHYL-3-(TRIFLUOROMETHYL)PHENETHYLAMINE HYDROCHLORIDE |
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