NOVEL CATIONIC LIPID COMPOUND

The present invention relates to a lipid compound, which can be used alone, or can be used in combination with other lipid components such as neutral lipids, charged lipids, steroids and/or analogues thereof, and/or polymer-conjugated lipids to form a lipid nanoparticle for delivering a therapeutic agent and/or a prophylactic agent. In some examples, the lipid nanoparticle is used for delivering nucleic acids, such as a messenger RNA and/or an antisense RNA. Further provided is a method for treating and/or preventing various diseases by means of using such lipid nanoparticles. In one embodiment, provided is a compound with a structure of formula (I) as shown below: or a salt, an isomer or a N-oxide thereof, wherein R1 is as defined herein. Also provided is a pharmaceutical composition comprising one or more compounds of structural formula (I) above and a therapeutic agent and/or a prophylactic agent. In some embodiments, the pharmaceutical composition also comprises one or more components selected from neutra