COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES

Provided herein are compounds and compositions for treating, managing or preventing coronaviral related diseases. In particular, provided herein are compounds which are inhibitors of SARS-CoV-2 main protease (Mpro), pharmaceutical compositions comprising such compounds, method for synthesizing such...

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Hauptverfasser:	HESSE, Matthew James, KIRRANE JR., Thomas Martin, SHI, Lei, YUAN, Jun, HORNAK, Viktor, JOSEPH, Sajan, MIAO, Yanan, ZHANG, Teng, LIN, Haiyao, LIU, Bo, MOSER, Heinz Ernst, PAPILLON, Julien, BAO, Denghui, GUO, Fengfeng, QU, Yang
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided herein are compounds and compositions for treating, managing or preventing coronaviral related diseases. In particular, provided herein are compounds which are inhibitors of SARS-CoV-2 main protease (Mpro), pharmaceutical compositions comprising such compounds, method for synthesizing such compounds and methods of using such compounds and compositions for the treatment, management or prevention of coronaviral related diseases. L'invention concerne des composés et des compositions pour le traitement, la gestion ou la prévention de maladies associées au coronavirus. En particulier, l'invention concerne des composés qui sont des inhibiteurs de la protéase principale du SARS-CoV-2 (Mpro), des compositions pharmaceutiques comprenant de tels composés, un procédé de synthèse de tels composés et des procédés d'utilisation de ces composés et de ces compositions pour le traitement, la gestion ou la prévention de maladies associées au coronavirus.