A CRYSTALLINE POTASSIUM SALT OF 1-ETHYL- N -((1,2,3,5,6,7-HEXAHYDRO- S -INDACEN-4-YL)CARBAMOYL)PIPERIDINE-4 -SULFONAMIDE
The present invention relates to a crystalline potassium salt of 1-ethyl-N-((1,2,3,5,6,7- hexahydro-s-indacen-4-yl)carbamoyl)piperidine-4-sulfonamide and to hydrates, solvates and polymorphic forms thereof. The present invention further relates to pharmaceutical compositions comprising this compound...
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| creator | WERMELINGER, Marc HIDBER, Pirmin ENKELMANN, Dennis Dimo |
| description | The present invention relates to a crystalline potassium salt of 1-ethyl-N-((1,2,3,5,6,7- hexahydro-s-indacen-4-yl)carbamoyl)piperidine-4-sulfonamide and to hydrates, solvates and polymorphic forms thereof. The present invention further relates to pharmaceutical compositions comprising this compound and the use of this compound in the treatment and prevention of medical diseases, disorders and conditions, most especially by NLRP3 inhibition.
La présente invention concerne un sel de potassium cristallin de 1-éthyl-N-((1,2,3,5-hexahydro-s-indacèn-4-yl))carbamoyl)pipéridine-4-sulfonamide et ses hydrates, solvates et formes polymorphes. La présente invention concerne en outre des compositions pharmaceutiques comprenant ce composé et l'utilisation de ce composé dans le traitement et la prévention de maladies, troubles et états de santé, plus particulièrement par inhibition de NLRP3. |
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La présente invention concerne un sel de potassium cristallin de 1-éthyl-N-((1,2,3,5-hexahydro-s-indacèn-4-yl))carbamoyl)pipéridine-4-sulfonamide et ses hydrates, solvates et formes polymorphes. La présente invention concerne en outre des compositions pharmaceutiques comprenant ce composé et l'utilisation de ce composé dans le traitement et la prévention de maladies, troubles et états de santé, plus particulièrement par inhibition de NLRP3.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221229&DB=EPODOC&CC=WO&NR=2022269010A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221229&DB=EPODOC&CC=WO&NR=2022269010A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WERMELINGER, Marc</creatorcontrib><creatorcontrib>HIDBER, Pirmin</creatorcontrib><creatorcontrib>ENKELMANN, Dennis Dimo</creatorcontrib><title>A CRYSTALLINE POTASSIUM SALT OF 1-ETHYL- N -((1,2,3,5,6,7-HEXAHYDRO- S -INDACEN-4-YL)CARBAMOYL)PIPERIDINE-4 -SULFONAMIDE</title><description>The present invention relates to a crystalline potassium salt of 1-ethyl-N-((1,2,3,5,6,7- hexahydro-s-indacen-4-yl)carbamoyl)piperidine-4-sulfonamide and to hydrates, solvates and polymorphic forms thereof. The present invention further relates to pharmaceutical compositions comprising this compound and the use of this compound in the treatment and prevention of medical diseases, disorders and conditions, most especially by NLRP3 inhibition.
La présente invention concerne un sel de potassium cristallin de 1-éthyl-N-((1,2,3,5-hexahydro-s-indacèn-4-yl))carbamoyl)pipéridine-4-sulfonamide et ses hydrates, solvates et formes polymorphes. La présente invention concerne en outre des compositions pharmaceutiques comprenant ce composé et l'utilisation de ce composé dans le traitement et la prévention de maladies, troubles et états de santé, plus particulièrement par inhibition de NLRP3.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjLEKwjAUALs4iPoPD1wq5EGb1orjs01pIE1Kk6KdSpE4iRbq4Ofr4Ac43Q3HLYM3Qd721pFSUgtojCNrZVeDJeXAlBCjcFWvEDRgGMaMs4TtWcYOWIkLVX3RGgQLKHVBudCYYq92ObUnqs3XGtmIVhbfN6aAtlOl0VTLQqyDxW28z37z4yrYlsLlFfrpOfh5Gq_-4V_D2fCIc54doziiOPmv-gA9HzjN</recordid><startdate>20221229</startdate><enddate>20221229</enddate><creator>WERMELINGER, Marc</creator><creator>HIDBER, Pirmin</creator><creator>ENKELMANN, Dennis Dimo</creator><scope>EVB</scope></search><sort><creationdate>20221229</creationdate><title>A CRYSTALLINE POTASSIUM SALT OF 1-ETHYL- N -((1,2,3,5,6,7-HEXAHYDRO- S -INDACEN-4-YL)CARBAMOYL)PIPERIDINE-4 -SULFONAMIDE</title><author>WERMELINGER, Marc ; HIDBER, Pirmin ; ENKELMANN, Dennis Dimo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2022269010A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>WERMELINGER, Marc</creatorcontrib><creatorcontrib>HIDBER, Pirmin</creatorcontrib><creatorcontrib>ENKELMANN, Dennis Dimo</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WERMELINGER, Marc</au><au>HIDBER, Pirmin</au><au>ENKELMANN, Dennis Dimo</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>A CRYSTALLINE POTASSIUM SALT OF 1-ETHYL- N -((1,2,3,5,6,7-HEXAHYDRO- S -INDACEN-4-YL)CARBAMOYL)PIPERIDINE-4 -SULFONAMIDE</title><date>2022-12-29</date><risdate>2022</risdate><abstract>The present invention relates to a crystalline potassium salt of 1-ethyl-N-((1,2,3,5,6,7- hexahydro-s-indacen-4-yl)carbamoyl)piperidine-4-sulfonamide and to hydrates, solvates and polymorphic forms thereof. The present invention further relates to pharmaceutical compositions comprising this compound and the use of this compound in the treatment and prevention of medical diseases, disorders and conditions, most especially by NLRP3 inhibition.
La présente invention concerne un sel de potassium cristallin de 1-éthyl-N-((1,2,3,5-hexahydro-s-indacèn-4-yl))carbamoyl)pipéridine-4-sulfonamide et ses hydrates, solvates et formes polymorphes. La présente invention concerne en outre des compositions pharmaceutiques comprenant ce composé et l'utilisation de ce composé dans le traitement et la prévention de maladies, troubles et états de santé, plus particulièrement par inhibition de NLRP3.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | A CRYSTALLINE POTASSIUM SALT OF 1-ETHYL- N -((1,2,3,5,6,7-HEXAHYDRO- S -INDACEN-4-YL)CARBAMOYL)PIPERIDINE-4 -SULFONAMIDE |
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