INTERLEUKIN-15 BASED IMMUNOCYTOKINES

The present invention inter alia relates to immunocytokines involving IL-15 superagonists (based on IL-15 and the sushi domain of IL-15Rα) and an antibody. The invention also provides nucleic acids, vectors, methods and medical uses. La présente invention concerne, entre autres, des immunocytokines...

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Bibliographische Detailangaben
Hauptverfasser:	BAMMERT, Lukas, PECHOUCKOVÁ, Sárka, NEDVEDOVA, Eva, KYRYCH SADILKOVA, Lenka, ADKINS, Irena, WALDMEIER, Lorenz, HOSKOVÁ, Simona, DE MARTYNOFF, Guy Luc Michel, BEERLI, Roger Renzo, VALENTOVÁ, Iva, MOEBIUS, Ulrich, BÉCHARD, David, ANTOSOVÁ, Zuzana
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention inter alia relates to immunocytokines involving IL-15 superagonists (based on IL-15 and the sushi domain of IL-15Rα) and an antibody. The invention also provides nucleic acids, vectors, methods and medical uses. La présente invention concerne, entre autres, des immunocytokines impliquant des superagonistes d'IL-15 (à base d'IL-15 et du domaine sushi de l'IL-15Rα) et un anticorps. L'invention concerne également des acides nucléiques, des vecteurs, des méthodes et des utilisations médicales.