NOVEL TRI-SPECIFIC BINDING MOLECULES

The present invention relates to novel tri-specific binding molecules. The invention also relates to nucleic acids encoding such binding molecules; to methods for preparing such binding molecules; to host cells expressing or capable of expressing such binding molecules; to compositions comprising su...

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Hauptverfasser: ADAM, Paul, SHAABAN, Abdulsalam, MACK, Taneisha Ann-Tanara, HEIDER, Karl-Heinz, OSTERMANN, Elinborg Katrin, KUENKELE, Klaus-Peter, WERNITZNIG, Andreas, GUPTA, Pankaj, WEISMANN, David, KASTURIRANGAN, Srinath, YOUNG, David S, GORMAN, Philip Nicholas, GUPTA, Priyanka, KONOPITZKY, Renate, KUMAR, Sandeep, COMEAU, Stephen R
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention relates to novel tri-specific binding molecules. The invention also relates to nucleic acids encoding such binding molecules; to methods for preparing such binding molecules; to host cells expressing or capable of expressing such binding molecules; to compositions comprising such binding molecules; and to uses of such binding molecules or such compositions, in particular for therapeutic purposes in the field of cancer diseases. La présente invention concerne de nouvelles molécules de liaison tri-spécifiques. L'invention concerne également des acides nucléiques codant pour de telles molécules de liaison; des procédés de préparation de telles molécules de liaison ; des cellules hôtes exprimant ou capables d'exprimer de telles molécules de liaison ; des compositions comprenant de telles molécules de liaison ; et des utilisations de telles molécules de liaison ou de telles compositions, en particulier à des fins thérapeutiques dans le domaine des maladies cancéreuses.