SYNTHESIS OF A NOVEL GLUCOSE-CONJUGATED METHOTREXATE AND ITS APPLICATION FOR THE TREATMENT AND PREVENTION OF NEOPLASMS

The subject of the invention is a new methotrexate-glucose conjugate derivative, its synthesis, and its use in the treatment and prevention of neoplasms, preferably in the treatment and prevention of neoplasms selected from: skin cancer, colorectal cancer, breast cancer, gastric cancer, sarcoma and...

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Hauptverfasser: ZIÓŁKOWSKI, Piotr, AGRAWAL, Siddarth, WOŹNIAK, Marta, WIŚNIEWSKI, Jerzy, MAKUCH, Sebastian, KRAWCZYK, Monika, GAMIAN, Andrzej, PASTUCH-GAWOŁEK, Gabriela, SZEJA, Wiesław
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creator ZIÓŁKOWSKI, Piotr
AGRAWAL, Siddarth
WOŹNIAK, Marta
WIŚNIEWSKI, Jerzy
MAKUCH, Sebastian
KRAWCZYK, Monika
GAMIAN, Andrzej
PASTUCH-GAWOŁEK, Gabriela
SZEJA, Wiesław
description The subject of the invention is a new methotrexate-glucose conjugate derivative, its synthesis, and its use in the treatment and prevention of neoplasms, preferably in the treatment and prevention of neoplasms selected from: skin cancer, colorectal cancer, breast cancer, gastric cancer, sarcoma and lung cancer. L'invention a pour objet un nouveau dérivé conjugué méthotrexate-glucose, sa synthèse, et son utilisation dans le traitement et la prévention de néoplasmes, de préférence dans le traitement et la prévention de néoplasmes choisis parmi : le cancer de la peau, le cancer colorectal, le cancer du sein, le cancer gastrique, le sarcome et le cancer du poumon.
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subjects CHEMISTRY
DERIVATIVES THEREOF
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
title SYNTHESIS OF A NOVEL GLUCOSE-CONJUGATED METHOTREXATE AND ITS APPLICATION FOR THE TREATMENT AND PREVENTION OF NEOPLASMS
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