METHODS AND COMPOSITIONS FOR TREATMENT OF AUTOIMMUNE CONDITIONS

The current disclosure provides methods and composition for treatment of autoimmune and inflammatory conditions, including systemic lupus erythematosus and antiphospholipid syndrome. Certain aspects of the disclosure are directed to methods for treatment of an autoimmune or inflammatory condition co...

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Bibliographische Detailangaben
Hauptverfasser:	LACKNER, Karl, RUF, Wolfram, WEINMANN-MENKE, Julia, MÜLLER-CALLEJA, Nadine
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TESTING
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Beschreibung
Zusammenfassung:	The current disclosure provides methods and composition for treatment of autoimmune and inflammatory conditions, including systemic lupus erythematosus and antiphospholipid syndrome. Certain aspects of the disclosure are directed to methods for treatment of an autoimmune or inflammatory condition comprising administering a composition comprising a therapeutically effective amount of NAPc2 or NAPc2/proline. Further aspects include pharmaceutical compositions comprising NAPc2 or NAPc2/proline and, in some cases, one or more additional anti-inflammatory agents. La présente divulgation concerne des procédés et une composition de traitement d'états auto-immuns et inflammatoires, comprenant le lupus érythémateux systémique et le syndrome des antiphospholipides. Certains aspects de la divulgation sont dirigés vers des procédés de traitement d'un état auto-immun ou inflammatoire comprenant l'administration d'une composition comprenant une quantité thérapeutiquement efficace de NAPc2 ou NAPc2/proline. Des aspects supplémentaires comprennent des compositions pharmaceutiques comprenant du NAPc2 ou NAPc2/proline et, dans certains cas, un ou plusieurs agents anti-inflammatoires additionnels.