CAMPTOTHECIN ANALOGUES, CONJUGATES AND METHODS OF USE

CAMPTOTHECIN ANALOGUES, CONJUGATES AND METHODS OF USE

Camptothecin analogues of Formula (I) and conjugates comprising the camptothecin analogues are described. The camptothecin analogues and conjugates may be used as therapeutic agents, particularly in the treatment of cancer, an autoimmune disease or a viral infection. L'invention concerne des an...

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Bibliographische Detailangaben
Hauptverfasser: RICH, James R, BRANT, Michael G, LASALLE, Manuel Michel Auguste, BARNSCHER, Stuart Daniel, PETERSEN, Mark Edmund, COLOMBO, Raffaele, DAS, Samir
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Camptothecin analogues of Formula (I) and conjugates comprising the camptothecin analogues are described. The camptothecin analogues and conjugates may be used as therapeutic agents, particularly in the treatment of cancer, an autoimmune disease or a viral infection. L'invention concerne des analogues de camptothécine de formule (I) et des conjugués comprenant les analogues de camptothécine. Les analogues et les conjugués de camptothécine peuvent être utilisés en tant qu'agents thérapeutiques, en particulier dans le traitement du cancer, d'une maladie auto-immune ou d'une infection virale.