FORMULATIONS OF 3-((3-(4-(2-(ISOBUTYLSULFONYL)PHENOXY)-3-(TRIFLUOROMETHYL)PHENYL)-1,2,4-OXADIAZOL-5-YL)METHYL)-5,5-DIMETHYL-1-(2-MORPHOLINOETHYL)IMIDAZOLIDINE-2,4-DIONE

Formulations of 3-((3-(4-(2-(isobutylsulfonyl)phenoxy)-3-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)methyl)-5,5-dimethyl-1-(2-morpholinoethyl)imidazolidine-2,4-dione and pharmaceutically acceptable salts thereof, processes for their production, and uses thereof, including in the treatment of ocul...

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Hauptverfasser:	SMITH, Jeffrey, SHAW, Duncan, HARDY, Declan, LAKSHMAN, Jay Parthiban, LOREN, Jon Christopher, RAYABANDLA, Sunil Kumar Mandala, RIDRUEJO, Nuria Jimenez, FAN, Yi, MOLTENI, Valentina, HUANG, Zhihong, TOWLER, Christopher Stephen
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:	Formulations of 3-((3-(4-(2-(isobutylsulfonyl)phenoxy)-3-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)methyl)-5,5-dimethyl-1-(2-morpholinoethyl)imidazolidine-2,4-dione and pharmaceutically acceptable salts thereof, processes for their production, and uses thereof, including in the treatment of ocular diseases and disorders such as dry eye disease and Meibomian gland dysfunction (MGD). Formulations de 3-((3-(4-(2-(isobutylsulfonyl)phénoxy)-3-(trifluorométhyl)phényl)-1,2,4-oxadiazol-5-yl)méthyl)-5,5-diméthyl-1-(2-morpholinoéthyl)imidazolidine-2,4-dione et de sels de qualité pharmaceutique de celle-ci, procédés pour leur production, et leurs utilisations, y compris dans le traitement de maladies et de troubles oculaires tels que le syndrome de l'œil sec 5 et un dysfonctionnement des glandes de Meibomius.