A SYRINGE-PLUG AND A CARTRIDGE FOR ANALYTIC ASSAYS COMPRISING SUCH A SYRINGE-PLUG

A syringe-plug (1, 1a, 1b, 1c, 1d) for placement in a sample chamber inlet of a cartridge for analytic assays, the syringe-plug comprising a tank (2) pre-filled with a liquid, the tank (2) having a proximal end (2a) and a distal end (2b), the proximal end (2a) of the tank (2) being closed by a piston (3) movable towards said distal end (2b), the distal end (2b) of the tank (2) being closed by a pierceable membrane (6) and the piston (3) being provided on its distal end (2b) side with a rod (4) having a piercing part (5) at its end enabling to pierce the membrane (6), wherein the proximal end (2a) of the tank (2) is provided with a plug part (7) surrounding the proximal end (2a) of the tank (2), the plug part (7) comprising external sealing means in the form of: at least one retaining rib (7b) surrounding a part of the plug part (7) circumference and comprising at least one gap (8b); at least one sealing rib (7c) surrounding the whole plug part (7) circumference; a thrust flange (7d) extending to the outside of the plug part (7) by a distance larger than the retaining rib(s) (7b) and the sealing rib(s) (7c), said sealing means being arranged sequentially as seen from the distal end (2b) side of the tank (2). A cartridge (11) for analytic assays comprising a sample chamber (10, 10a) integrated with a microfluidic system (9), the microfluidic system (9) being fed with a sample of analyte (S) and with a separating liquid (L), the sample chamber (10, 10a) having an inlet (13) adapted for insertion of the sample of analyte (S), and the cartridge further comprising a syringe-plug according to the invention. L'invention concerne un bouchon de seringue (1, 1a, 1b, 1c, 1d) destiné à être placé dans une entrée de chambre d'échantillon d'une cartouche pour des dosages analytiques, le bouchon de seringue comprenant un réservoir (2) pré-remplie d'un liquide, le réservoir (2) ayant une extrémité proximale (2a) et une extrémité distale (2b), l'extrémité proximale (2a) du réservoir (2) étant fermée par un piston (3) mobile vers ladite extrémité distale (2b), l'extrémité distale (2b) du réservoir (2) étant fermée par une membrane perçable (6) et le piston (3) étant disposée sur son extrémité distale (2b) avec une tige (4) ayant une partie de perçage (5) à son extrémité permettant de percer la membrane (6), l'extrémité proximale (2a) du réservoir (2) est pourvue d'une partie de bouchon (7) entourant l'extrémité proximale (2a) du réservoir (2), la partie de bouchon (7) compre