METHODS OF USING ANTI-CD79B IMMUNOCONJUGATES TO TREAT DIFFUSE LARGE B-CELL LYMPHOMA

Provided herein are methods of treating B-cell proliferative disorders (such as diffuse large B-cell lymphoma "DLBCL") using immunoconjugates comprising anti-CD79b antibodies in combination with an immunomodulatory agent (such as lenalidomide) and an anti-CD20 antibody (such as obinutuzuma...

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Bibliographische Detailangaben
Hauptverfasser:	MUSICK, Lisa Linnea, HIRATA, Jamie Harue
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided herein are methods of treating B-cell proliferative disorders (such as diffuse large B-cell lymphoma "DLBCL") using immunoconjugates comprising anti-CD79b antibodies in combination with an immunomodulatory agent (such as lenalidomide) and an anti-CD20 antibody (such as obinutuzumab or rituximab). L'invention concerne des méthodes de traitement de troubles prolifératifs à lymphocytes B (tels que le lymphome diffus à grandes cellules B, "DLBCL") à l'aide d'immuno-conjugués comprenant des anticorps anti-CD79b en combinaison avec un agent immunomodulateur (comme le lénalidomide) et un anticorps anti-CD20 (comme l'obinutuzumab ou le rituximab).