NF-KB AS BIOMARKER FOR ASSESSING TREATMENT EFFICACY IN PARKINSON'S DISEASE

Provided are methods for monitoring the progression of Parkinson's Disease, and methods for monitoring or determining the effectiveness of therapeutics for the treatment of Parkinson's Disease, as well as methods for treatment thereof, by assessing one or more biomarkers, such as NF-κB and...

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Bibliographische Detailangaben
Hauptverfasser:	GENDELMAN, Howard, MOSTAFA, Mai, MOSLEY, R. Lee, OLSON, Katherine
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
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Beschreibung
Zusammenfassung:	Provided are methods for monitoring the progression of Parkinson's Disease, and methods for monitoring or determining the effectiveness of therapeutics for the treatment of Parkinson's Disease, as well as methods for treatment thereof, by assessing one or more biomarkers, such as NF-κB and/or calcineurin. L'invention concerne des méthodes de surveillance de la progression de la maladie de Parkinson, et des méthodes de surveillance ou de détermination de l'efficacité d'agents thérapeutiques pour le traitement de la maladie de Parkinson, ainsi que des méthodes de traitement associés, par évaluation d'un ou de plusieurs biomarqueurs, tels que le NF-κB et/ou la calcineurine.