METHOD FOR TREATING CANCER BY USING ANTIBODY-DRUG CONJUGATE AND USE

The present invention belongs to the technical field of biomedicine, and relates to a method for treating cancer by using an antibody-drug conjugate. In particular, the present invention relates to a use of an antibody drug conjugate represented by formula (I) and a pharmaceutically acceptable salt, a stereoisomer or a metabolite thereof, or a solvate of the foregoing in the preparation of a drug for preventing and/or treating a HER2-expressing, amplified or mutated cancer, wherein A is a group obtained by removing n amino groups from an antibody against HER2 or an active fragment or variant thereof; preferably, A is trastuzumab or a group obtained by removing n amino groups from Pertuzumab; n is selected from 1-10, such as 2-10 or 2-8; and preferably, n is an integer of 1, 2, 3, 4, 5, 6, 7 or 8. La présente invention se rapporte au domaine technique de la biomédecine, et concerne une méthode de traitement du cancer à l'aide d'un conjugué anticorps-médicament. En particulier, la présente invention concerne un