USE OF FLUORESCEIN DICARBONATE DERIVATIVES AS A CELL MARKER
The invention relates to fluorescein derivative compounds and the use thereof as fluorescent markers. Said markers can be used in particular in biology and in medicine, particularly in the field of ophthalmology. The non-fluorescent fluorescein derivatives are activated in the cell, thereby allowing...
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| creator | GAIN, Philippe MARET, Corentin HE, Zhiguo ULRICH, Gilles DE NICOLA, Antoinette THURET, Gilles MAURIN, Corantin COURRIER, Emilie |
| description | The invention relates to fluorescein derivative compounds and the use thereof as fluorescent markers. Said markers can be used in particular in biology and in medicine, particularly in the field of ophthalmology. The non-fluorescent fluorescein derivatives are activated in the cell, thereby allowing the detection of living cells as well as the quantification of cell viability by fluorescence, without being toxic to cells.
La présente invention concerne des composés dérivés de fluorescéine, et leur utilisation en tant que marqueurs fluorescents. Ils peuvent notamment être utilisés en biologie et en médecine, particulièrement dans le domaine de l'ophtalmologie. Les dérivés de fluorescéine non-fluorescents sont activés dans la cellule permettant alors la détection des cellules vivantes ainsi que la quantification de la viabilité cellulaire grâce à la fluorescence, et en absence de toxicité cellulaire. |
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La présente invention concerne des composés dérivés de fluorescéine, et leur utilisation en tant que marqueurs fluorescents. Ils peuvent notamment être utilisés en biologie et en médecine, particulièrement dans le domaine de l'ophtalmologie. Les dérivés de fluorescéine non-fluorescents sont activés dans la cellule permettant alors la détection des cellules vivantes ainsi que la quantification de la viabilité cellulaire grâce à la fluorescence, et en absence de toxicité cellulaire.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; ENZYMOLOGY ; HETEROCYCLIC COMPOUNDS ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221103&DB=EPODOC&CC=WO&NR=2022229353A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221103&DB=EPODOC&CC=WO&NR=2022229353A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GAIN, Philippe</creatorcontrib><creatorcontrib>MARET, Corentin</creatorcontrib><creatorcontrib>HE, Zhiguo</creatorcontrib><creatorcontrib>ULRICH, Gilles</creatorcontrib><creatorcontrib>DE NICOLA, Antoinette</creatorcontrib><creatorcontrib>THURET, Gilles</creatorcontrib><creatorcontrib>MAURIN, Corantin</creatorcontrib><creatorcontrib>COURRIER, Emilie</creatorcontrib><title>USE OF FLUORESCEIN DICARBONATE DERIVATIVES AS A CELL MARKER</title><description>The invention relates to fluorescein derivative compounds and the use thereof as fluorescent markers. Said markers can be used in particular in biology and in medicine, particularly in the field of ophthalmology. The non-fluorescent fluorescein derivatives are activated in the cell, thereby allowing the detection of living cells as well as the quantification of cell viability by fluorescence, without being toxic to cells.
La présente invention concerne des composés dérivés de fluorescéine, et leur utilisation en tant que marqueurs fluorescents. Ils peuvent notamment être utilisés en biologie et en médecine, particulièrement dans le domaine de l'ophtalmologie. Les dérivés de fluorescéine non-fluorescents sont activés dans la cellule permettant alors la détection des cellules vivantes ainsi que la quantification de la viabilité cellulaire grâce à la fluorescence, et en absence de toxicité cellulaire.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>ENZYMOLOGY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAODXZV8HdTcPMJ9Q9yDXZ29fRTcPF0dgxy8vdzDHFVcHEN8gxzDPEMcw1WcAQiBWdXHx8FX8cgb9cgHgbWtMSc4lReKM3NoOzmGuLsoZtakB-fWlyQmJyal1oSH-5vZGAEBJbGpsaOhsbEqQIAYicp6A</recordid><startdate>20221103</startdate><enddate>20221103</enddate><creator>GAIN, Philippe</creator><creator>MARET, Corentin</creator><creator>HE, Zhiguo</creator><creator>ULRICH, Gilles</creator><creator>DE NICOLA, Antoinette</creator><creator>THURET, Gilles</creator><creator>MAURIN, Corantin</creator><creator>COURRIER, Emilie</creator><scope>EVB</scope></search><sort><creationdate>20221103</creationdate><title>USE OF FLUORESCEIN DICARBONATE DERIVATIVES AS A CELL MARKER</title><author>GAIN, Philippe ; MARET, Corentin ; HE, Zhiguo ; ULRICH, Gilles ; DE NICOLA, Antoinette ; THURET, Gilles ; MAURIN, Corantin ; COURRIER, Emilie</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2022229353A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>ENZYMOLOGY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>GAIN, Philippe</creatorcontrib><creatorcontrib>MARET, Corentin</creatorcontrib><creatorcontrib>HE, Zhiguo</creatorcontrib><creatorcontrib>ULRICH, Gilles</creatorcontrib><creatorcontrib>DE NICOLA, Antoinette</creatorcontrib><creatorcontrib>THURET, Gilles</creatorcontrib><creatorcontrib>MAURIN, Corantin</creatorcontrib><creatorcontrib>COURRIER, Emilie</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GAIN, Philippe</au><au>MARET, Corentin</au><au>HE, Zhiguo</au><au>ULRICH, Gilles</au><au>DE NICOLA, Antoinette</au><au>THURET, Gilles</au><au>MAURIN, Corantin</au><au>COURRIER, Emilie</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>USE OF FLUORESCEIN DICARBONATE DERIVATIVES AS A CELL MARKER</title><date>2022-11-03</date><risdate>2022</risdate><abstract>The invention relates to fluorescein derivative compounds and the use thereof as fluorescent markers. Said markers can be used in particular in biology and in medicine, particularly in the field of ophthalmology. The non-fluorescent fluorescein derivatives are activated in the cell, thereby allowing the detection of living cells as well as the quantification of cell viability by fluorescence, without being toxic to cells.
La présente invention concerne des composés dérivés de fluorescéine, et leur utilisation en tant que marqueurs fluorescents. Ils peuvent notamment être utilisés en biologie et en médecine, particulièrement dans le domaine de l'ophtalmologie. Les dérivés de fluorescéine non-fluorescents sont activés dans la cellule permettant alors la détection des cellules vivantes ainsi que la quantification de la viabilité cellulaire grâce à la fluorescence, et en absence de toxicité cellulaire.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY HETEROCYCLIC COMPOUNDS MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE |
| title | USE OF FLUORESCEIN DICARBONATE DERIVATIVES AS A CELL MARKER |
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