USE OF FLUORESCEIN DICARBONATE DERIVATIVES AS A CELL MARKER

USE OF FLUORESCEIN DICARBONATE DERIVATIVES AS A CELL MARKER

The invention relates to fluorescein derivative compounds and the use thereof as fluorescent markers. Said markers can be used in particular in biology and in medicine, particularly in the field of ophthalmology. The non-fluorescent fluorescein derivatives are activated in the cell, thereby allowing...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GAIN, Philippe, MARET, Corentin, HE, Zhiguo, ULRICH, Gilles, DE NICOLA, Antoinette, THURET, Gilles, MAURIN, Corantin, COURRIER, Emilie
Format: Patent
Sprache:eng ; fre
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
HETEROCYCLIC COMPOUNDS
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:The invention relates to fluorescein derivative compounds and the use thereof as fluorescent markers. Said markers can be used in particular in biology and in medicine, particularly in the field of ophthalmology. The non-fluorescent fluorescein derivatives are activated in the cell, thereby allowing the detection of living cells as well as the quantification of cell viability by fluorescence, without being toxic to cells. La présente invention concerne des composés dérivés de fluorescéine, et leur utilisation en tant que marqueurs fluorescents. Ils peuvent notamment être utilisés en biologie et en médecine, particulièrement dans le domaine de l'ophtalmologie. Les dérivés de fluorescéine non-fluorescents sont activés dans la cellule permettant alors la détection des cellules vivantes ainsi que la quantification de la viabilité cellulaire grâce à la fluorescence, et en absence de toxicité cellulaire.