INTRACELLULAR DELIVERY COMPOSITIONS

Protein conjugates comprising a protein carrier comprising polyethylenimine, a payload that interacts with an intracellular target and a linker are provided. Pharmaceutical composition comprising the protein conjugates as well as methods of using and producing the protein conjugates are also provide...

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Bibliographische Detailangaben
Hauptverfasser:	SHILOVITZKY, Orit, LEWKOWICZ, Ayala, HAKIM, Motti, FAYGENBOIM-ORNAI, Rotem, GOTTFRIED, Yossi, CHEN ZELTSBURG, Lilach, UZAN GUETA, Rozi Ravit, SAPIR, Yair, MANDEL, Ilana, SHULMAN, Avidor, BEN-MOSHE, Tehila
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Protein conjugates comprising a protein carrier comprising polyethylenimine, a payload that interacts with an intracellular target and a linker are provided. Pharmaceutical composition comprising the protein conjugates as well as methods of using and producing the protein conjugates are also provided. L'invention concerne des conjugués de protéine comprenant un support de protéine présentant de la polyéthylènimine, une charge utile qui interagit avec une cible intracellulaire et un lieur. L'invention concerne également une composition pharmaceutique comprenant les conjugués de protéines ainsi que des méthodes d'utilisation et de production des conjugués de protéines.