ANTI-VIRAL AND ANTI-TUMORAL COMPOUNDS, AND USES THEREOF

Disclosed herein are 3, 4-didehydro- and 3'-deoxy-3, 4-didehydro-compounds, and pharmaceutical compositions thereof. The 3, 4-didehydro- and 3'-deoxy-3, 4- didehydro-compounds, and pharmaceutical compositions thereof may be used in methods of treating diseases including virus-induced disea...

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Bibliographische Detailangaben
Hauptverfasser:	SHOMAR MONGES, Helena, MACHLENKIN, Arthur, EISENBERG, Eugene J, SPERANDIO, David
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Disclosed herein are 3, 4-didehydro- and 3'-deoxy-3, 4-didehydro-compounds, and pharmaceutical compositions thereof. The 3, 4-didehydro- and 3'-deoxy-3, 4- didehydro-compounds, and pharmaceutical compositions thereof may be used in methods of treating diseases including virus-induced diseases, cancer, autoimmune diseases, immune disorders, and bacterial-associated diseases or infections, or combinations thereof. Examples of viral-induced diseases include viral infections by RNA or DNA viruses, for example SARS-CoV-2, EBV, and BKV. L'invention concerne des composés 3, 4-didéshydro et 3'-désoxy-3, 4-didéshydro, et leurs compositions pharmaceutiques. Les composés 3, 4-didéshydro et 3'-désoxy-3, 4-didéshydro, et leurs compositions pharmaceutiques peuvent être utilisés dans des méthodes de traitement de maladies, y compris les maladies induites par des virus, le cancer, les maladies auto-immunes, les troubles immunitaires et les maladies ou infections associées à des bactéries, ou leurs combinaisons. Parmi les exemples de maladies induites par des virus, citons les infections virales par des virus à ARN ou à ADN, par exemple le SRAS-CoV-2, l'EBV et le BKV.