CELL GEL PREPARATION FOR REDUCING SHEAR DAMAGE ON CELLS AND METHOD FOR REDUCING SHEAR DAMAGE ON CELLS

The present invention relates to a cell gel preparation, which is used for treating and/or preventing acute or chronic osteoarthritis and/or symptoms thereof by means of intra-articular injection, wherein the preparation comprises a nucleic acid hydrogel loading mesenchymal stem cells. The present i...

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Bibliographische Detailangaben
Hauptverfasser: YAN, Xin, LI, Yujie, ZHOU, Bini, YU, Jiakuo, YANG, Bo, LI, Xin, LIU, Dongsheng
Format: Patent
Sprache:chi ; eng ; fre
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Zusammenfassung:The present invention relates to a cell gel preparation, which is used for treating and/or preventing acute or chronic osteoarthritis and/or symptoms thereof by means of intra-articular injection, wherein the preparation comprises a nucleic acid hydrogel loading mesenchymal stem cells. The present invention further relates to a method for treating or preventing acute and chronic osteoarthrosis and associated symptoms caused by inflammation (especially osteoarticular pain and activity or function loss) by means of using the cell gel preparation, and a method for reducing the shear damage on cells in a shear environment by means of using the nucleic acid hydrogel. La présente invention concerne une préparation de gel cellulaire, qui est utilisée pour traiter et/ou prévenir l'arthrose aiguë ou chronique et/ou ses symptômes grâce à une injection intra-articulaire, la préparation comprenant un hydrogel d'acide nucléique chargé de cellules souches mésenchymateuses. La présente invention concerne en outre une méthod