COMPOSITIONS AND METHODS FOR TREATING A NEURODEGENERATIVE OR DEVELOPMENTAL DISORDER

The invention features compositions and methods for treating developmental, neurodevelopmental (e.g., Fragile X syndrome (FXS)) or Down syndrome (DS) or neurodegenerative disorders (e.g., Alzheimer's disease (AD)) by increasing expression of Fragile X Mental Retardation Protein (FMRP) in patien...

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Bibliographische Detailangaben
Hauptverfasser: BARRETT, Lindy, SUSCO, Sara G
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention features compositions and methods for treating developmental, neurodevelopmental (e.g., Fragile X syndrome (FXS)) or Down syndrome (DS) or neurodegenerative disorders (e.g., Alzheimer's disease (AD)) by increasing expression of Fragile X Mental Retardation Protein (FMRP) in patients having such disorders. L'invention concerne des compositions et des méthodes de traitement du développement, du neurodéveloppement (par exemple, du syndrome de l'X fragile (FXS)) ou du syndrome de Down (DS) ou de troubles neurodégénératifs (par exemple, la maladie d'Alzheimer (AD)) par l'augmentation de l'expression de la protéine de retard mental de l'X fragile (FMRP) chez des patients ayant de tels troubles.