MONOCLONAL ANTIBODY THAT SPECIFICALLY BINDS TO GD2

The present invention relates to the field of biotechnology and medicine, in particular to a monoclonal antibody or antigen-binding fragment thereof that specifically binds to GD2 (ganglioside GD2). The invention further relates to nucleic acids encoding said antibody, expression vectors, host cells...

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Bibliographische Detailangaben
Hauptverfasser:	IAKOVLEV, Pavel Andreevich, SAKHAROVA, Dina Khaidarovna, KONDINSKAIA, Diana Aleksandrovna, MOROZOV, Dmitry Valentinovich, SHIGINA, Valeriia Evgenevna, SOLOVYEV, Valery Vladimirovich, AGEEV, Sergei Andreevich, STOLYAROVA, Alina Konstantinovna, GREFENSHTEIN, Mariia Anatolevna, CHERNYKH, Yulia Sergeevna
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to the field of biotechnology and medicine, in particular to a monoclonal antibody or antigen-binding fragment thereof that specifically binds to GD2 (ganglioside GD2). The invention further relates to nucleic acids encoding said antibody, expression vectors, host cells and methods for producing same, methods for producing the antibodies according to the invention, pharmaceutical compositions comprising the antibody according to the invention, pharmaceutical compositions comprising the antibody according to the invention and other therapeutically active compounds, methods for treating diseases or disorders mediated by GD2, uses of the antibodies or pharmaceutical compositions thereof for treating diseases or disorders mediated by GD2, and uses of the antibodies and other therapeutically active compounds for treating diseases or disorders mediated by GD2. La présente invention concerne le domaine de la biotechnologie et de la médecine, en particulier un anticorps monoclonal ou un fragment de liaison à l'antigène de celui-ci se liant spécifiquement au GD2 (ganglioside GD2). L'invention concerne en outre des acides nucléiques codant pour ledit anticorps, vecteurs d'expression, cellules hôtes et leurs procédés de production, des procédés de production des anticorps selon l'invention, des compositions pharmaceutiques comprenant l'anticorps selon l'invention, des compositions pharmaceutiques comprenant l'anticorps selon l'invention et d'autres composés thérapeutiquement actifs, des méthodes de traitement de maladies ou de troubles médiés par GD2, des utilisations des anticorps ou des compositions pharmaceutiques de ceux-ci pour le traitement de maladies ou de troubles médiés par GD2, et les utilisations des anticorps et d'autres composés thérapeutiquement actifs pour le traitement de maladies ou de troubles médiés par GD2.