3'-[(2Z)-[1-(3,4-DIMETHYLPHENYL)-1,5-DIHYDRO-3-METHYL-5-OXO-4H-PYRAZOL-4-YLIDENE]HYDRAZINO]-2'-HYDROXY-[1,1'-BIPHENYL]-3-CARBOXYLIC ACID AND ITS SALTS FORMULATION

3'-[(2Z)-[1-(3,4-DIMETHYLPHENYL)-1,5-DIHYDRO-3-METHYL-5-OXO-4H-PYRAZOL-4-YLIDENE]HYDRAZINO]-2'-HYDROXY-[1,1'-BIPHENYL]-3-CARBOXYLIC ACID AND ITS SALTS FORMULATION

The present invention relates to an oral pharmaceutical formulation, suitably tablets, suitably capsules, comprising 3'-[(2Z)-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid (INN name eltrombopag) or a pha...

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Hauptverfasser: PATEL, Parthkumar, PATIDAR, Kanhaiyalal, ROYCE, Alan Edward, VELIP, Chandrakant, VERMA, Daya D, SHAIKH HAMID, Shaikh Mohsin, BORDAWEKAR, Mangesh Sadashiv
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Sprache:eng ; fre
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator PATEL, Parthkumar
PATIDAR, Kanhaiyalal
ROYCE, Alan Edward
VELIP, Chandrakant
VERMA, Daya D
SHAIKH HAMID, Shaikh Mohsin
BORDAWEKAR, Mangesh Sadashiv
description The present invention relates to an oral pharmaceutical formulation, suitably tablets, suitably capsules, comprising 3'-[(2Z)-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid (INN name eltrombopag) or a pharmaceutically acceptable salt thereof, wherein the oral pharmaceutical formulation is coated with an enteric coating. La présente invention concerne une formulation pharmaceutique orale, de façon appropriée des comprimés, de façon appropriée des gélules, comprenant du 3'-[(2Z)-[1-(3,4-diméthylphényl)-1,5-dihydro-3-méthyl-5-oxo-4H-pyrazol-4-ylidène]hydrazino]-2'-hydroxy-[1,1'-biphényl]-3-carboxylique (dénomination INN : eltrombopag) ou un sel pharmaceutiquement acceptable associé, la formulation pharmaceutique orale étant revêtue d'un enrobage entérique.
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HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title 3'-[(2Z)-[1-(3,4-DIMETHYLPHENYL)-1,5-DIHYDRO-3-METHYL-5-OXO-4H-PYRAZOL-4-YLIDENE]HYDRAZINO]-2'-HYDROXY-[1,1'-BIPHENYL]-3-CARBOXYLIC ACID AND ITS SALTS FORMULATION
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