MICRORNA-27B INHIBITORS

The present invention provides antisense oligonucleotides complementary to miR-27b, capable of potently inhibiting the activity of miR-27b. Such compounds are useful as pharmaceuticals for treatment of diseases in the CNS or in the PNS including neurological diseases. La présente invention concerne...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	KLITGAARD, Henrik Valdemar, KAUPPINEN, Markus Sakari, HANSEN, Stine Normann
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides antisense oligonucleotides complementary to miR-27b, capable of potently inhibiting the activity of miR-27b. Such compounds are useful as pharmaceuticals for treatment of diseases in the CNS or in the PNS including neurological diseases. La présente invention concerne des oligonucléotides antisens complémentaires de miR-27 b, capables d'inhiber puissamment l'activité de miR-27b. De tels composés sont utiles en tant que produits pharmaceutiques pour le traitement de maladies dans le SNC ou dans le SNP y compris des maladies neurologiques.