TETRAHYDROTHIENO PYRIDINE DERIVATIVES AS DDRS INHIBITORS

The present invention relates to compounds of general formula (I) inhibiting Discoidin Domain Receptors (DDR inhibitors), methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful for instance in the tre...

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Bibliographische Detailangaben
Hauptverfasser:	RIZZI, Andrea, MULLINS, Toby Matthew Grover, KARAWAJCZYK, Anna, KNIGHT, Keith Christopher, WHITTAKER, Ben Paul, RANCATI, Fabio, CARZANIGA, Laura, WOŁEK, Barbara Karolina
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to compounds of general formula (I) inhibiting Discoidin Domain Receptors (DDR inhibitors), methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful for instance in the treatment of many disorders associated with DDR mechanisms. La présente invention concerne des composés de formule générale (I) inhibant des récepteurs du domaine discoïdine (inhibiteurs DDR), des méthodes de préparation de tels composés, des compositions pharmaceutiques les contenant et leur utilisation thérapeutique. Les composés de l'invention peuvent être utiles, par exemple, dans le traitement de nombreux troubles associés à des mécanismes DDR.