THERAPEUTIC BINDING MOLECULES

The invention relates to binding molecules, such as antibodies, that bind to the chemokine receptor CCR9. More particularly, the invention relates to the treatment of CCR9-mediated diseases or conditions such as inflammatory bowel disease (IBD), and methods for the detection of CCR9, which make use...

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Hauptverfasser: REES, David Gareth, NYS, Josquin Arnaud, HUNTINGTON, Catherine Eugenie Chaillan, ROBINSON, Matthew, THOM, Albert George, CARIUK, Peter, RILEY, Aidan, SCHOFIELD, Darren Jonathan, IRVING, Lorraine
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creator REES, David Gareth
NYS, Josquin Arnaud
HUNTINGTON, Catherine Eugenie Chaillan
ROBINSON, Matthew
THOM, Albert George
CARIUK, Peter
RILEY, Aidan
SCHOFIELD, Darren Jonathan
IRVING, Lorraine
description The invention relates to binding molecules, such as antibodies, that bind to the chemokine receptor CCR9. More particularly, the invention relates to the treatment of CCR9-mediated diseases or conditions such as inflammatory bowel disease (IBD), and methods for the detection of CCR9, which make use of the binding molecules of the invention. L'invention concerne des molécules de liaison, telles que des anticorps, qui se lient au récepteur CCR9 de chimiokine. Plus particulièrement, l'invention concerne le traitement de maladies ou de pathologies à médiation par CCR9 telles qu'une maladie intestinale inflammatoire (IBD), et des méthodes de détection de CCR9, qui font appel aux molécules de liaison de l'invention.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title THERAPEUTIC BINDING MOLECULES
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