THERAPEUTIC BINDING MOLECULES

The invention relates to binding molecules, such as antibodies, that bind to the chemokine receptor CCR9. More particularly, the invention relates to the treatment of CCR9-mediated diseases or conditions such as inflammatory bowel disease (IBD), and methods for the detection of CCR9, which make use...

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Bibliographische Detailangaben
Hauptverfasser:	REES, David Gareth, NYS, Josquin Arnaud, HUNTINGTON, Catherine Eugenie Chaillan, ROBINSON, Matthew, THOM, Albert George, CARIUK, Peter, RILEY, Aidan, SCHOFIELD, Darren Jonathan, IRVING, Lorraine
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to binding molecules, such as antibodies, that bind to the chemokine receptor CCR9. More particularly, the invention relates to the treatment of CCR9-mediated diseases or conditions such as inflammatory bowel disease (IBD), and methods for the detection of CCR9, which make use of the binding molecules of the invention. L'invention concerne des molécules de liaison, telles que des anticorps, qui se lient au récepteur CCR9 de chimiokine. Plus particulièrement, l'invention concerne le traitement de maladies ou de pathologies à médiation par CCR9 telles qu'une maladie intestinale inflammatoire (IBD), et des méthodes de détection de CCR9, qui font appel aux molécules de liaison de l'invention.