BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER
The present invention provides new bicyclic tetrahydroazepine derivatives having the general formula (I), wherein X, Y, R1, R2, R3, R4, R5, R6, R6a are as defined herein, compositions including the compounds, processes of manufacturing the compounds and methods of using them in the treatment of canc...
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creator | BRITSCHGI, Adrian KUEHNE, Holger WICHMANN, Juergen BRANDSTAETTER, Marco LUEBBERS, Thomas MUELLER, Barbara Johanna HUTTER, Roman KUHN, Bernd MARTIN, Laetitia Janine |
description | The present invention provides new bicyclic tetrahydroazepine derivatives having the general formula (I), wherein X, Y, R1, R2, R3, R4, R5, R6, R6a are as defined herein, compositions including the compounds, processes of manufacturing the compounds and methods of using them in the treatment of cancer.
La présente invention concerne de nouveaux dérivés de tétrahydroazépine bicycliques de formule générale (I) dans laquelle X, Y, R1, R2, R3, R4, R5, R6, R6a sont tels que définis dans la description, des compositions comprenant les composés, des procédés de fabrication des composés et des procédés d'utilisation de ceux-ci dans le traitement du cancer. |
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La présente invention concerne de nouveaux dérivés de tétrahydroazépine bicycliques de formule générale (I) dans laquelle X, Y, R1, R2, R3, R4, R5, R6, R6a sont tels que définis dans la description, des compositions comprenant les composés, des procédés de fabrication des composés et des procédés d'utilisation de ceux-ci dans le traitement du cancer.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220818&DB=EPODOC&CC=WO&NR=2022171745A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220818&DB=EPODOC&CC=WO&NR=2022171745A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BRITSCHGI, Adrian</creatorcontrib><creatorcontrib>KUEHNE, Holger</creatorcontrib><creatorcontrib>WICHMANN, Juergen</creatorcontrib><creatorcontrib>BRANDSTAETTER, Marco</creatorcontrib><creatorcontrib>LUEBBERS, Thomas</creatorcontrib><creatorcontrib>MUELLER, Barbara Johanna</creatorcontrib><creatorcontrib>HUTTER, Roman</creatorcontrib><creatorcontrib>KUHN, Bernd</creatorcontrib><creatorcontrib>MARTIN, Laetitia Janine</creatorcontrib><title>BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER</title><description>The present invention provides new bicyclic tetrahydroazepine derivatives having the general formula (I), wherein X, Y, R1, R2, R3, R4, R5, R6, R6a are as defined herein, compositions including the compounds, processes of manufacturing the compounds and methods of using them in the treatment of cancer.
La présente invention concerne de nouveaux dérivés de tétrahydroazépine bicycliques de formule générale (I) dans laquelle X, Y, R1, R2, R3, R4, R5, R6, R6a sont tels que définis dans la description, des compositions comprenant les composés, des procédés de fabrication des composés et des procédés d'utilisation de ceux-ci dans le traitement du cancer.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHBy8nSOdPbxdFYIcQ0JcvSIdAnyd4xyDfD0c1VwcQ3yDHMM8QxzDVZw8w9SCPFwVQgJcnUM8XX1C1Hwd1NwdvRzdg3iYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXx4f5GBkZGhuaG5iamjobGxKkCAMz_LE4</recordid><startdate>20220818</startdate><enddate>20220818</enddate><creator>BRITSCHGI, Adrian</creator><creator>KUEHNE, Holger</creator><creator>WICHMANN, Juergen</creator><creator>BRANDSTAETTER, Marco</creator><creator>LUEBBERS, Thomas</creator><creator>MUELLER, Barbara Johanna</creator><creator>HUTTER, Roman</creator><creator>KUHN, Bernd</creator><creator>MARTIN, Laetitia Janine</creator><scope>EVB</scope></search><sort><creationdate>20220818</creationdate><title>BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER</title><author>BRITSCHGI, Adrian ; KUEHNE, Holger ; WICHMANN, Juergen ; BRANDSTAETTER, Marco ; LUEBBERS, Thomas ; MUELLER, Barbara Johanna ; HUTTER, Roman ; KUHN, Bernd ; MARTIN, Laetitia Janine</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2022171745A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BRITSCHGI, Adrian</creatorcontrib><creatorcontrib>KUEHNE, Holger</creatorcontrib><creatorcontrib>WICHMANN, Juergen</creatorcontrib><creatorcontrib>BRANDSTAETTER, Marco</creatorcontrib><creatorcontrib>LUEBBERS, Thomas</creatorcontrib><creatorcontrib>MUELLER, Barbara Johanna</creatorcontrib><creatorcontrib>HUTTER, Roman</creatorcontrib><creatorcontrib>KUHN, Bernd</creatorcontrib><creatorcontrib>MARTIN, Laetitia Janine</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BRITSCHGI, Adrian</au><au>KUEHNE, Holger</au><au>WICHMANN, Juergen</au><au>BRANDSTAETTER, Marco</au><au>LUEBBERS, Thomas</au><au>MUELLER, Barbara Johanna</au><au>HUTTER, Roman</au><au>KUHN, Bernd</au><au>MARTIN, Laetitia Janine</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER</title><date>2022-08-18</date><risdate>2022</risdate><abstract>The present invention provides new bicyclic tetrahydroazepine derivatives having the general formula (I), wherein X, Y, R1, R2, R3, R4, R5, R6, R6a are as defined herein, compositions including the compounds, processes of manufacturing the compounds and methods of using them in the treatment of cancer.
La présente invention concerne de nouveaux dérivés de tétrahydroazépine bicycliques de formule générale (I) dans laquelle X, Y, R1, R2, R3, R4, R5, R6, R6a sont tels que définis dans la description, des compositions comprenant les composés, des procédés de fabrication des composés et des procédés d'utilisation de ceux-ci dans le traitement du cancer.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER |
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