BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER

The present invention provides new bicyclic tetrahydroazepine derivatives having the general formula (I), wherein X, Y, R1, R2, R3, R4, R5, R6, R6a are as defined herein, compositions including the compounds, processes of manufacturing the compounds and methods of using them in the treatment of canc...

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Hauptverfasser: BRITSCHGI, Adrian, KUEHNE, Holger, WICHMANN, Juergen, BRANDSTAETTER, Marco, LUEBBERS, Thomas, MUELLER, Barbara Johanna, HUTTER, Roman, KUHN, Bernd, MARTIN, Laetitia Janine
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creator BRITSCHGI, Adrian
KUEHNE, Holger
WICHMANN, Juergen
BRANDSTAETTER, Marco
LUEBBERS, Thomas
MUELLER, Barbara Johanna
HUTTER, Roman
KUHN, Bernd
MARTIN, Laetitia Janine
description The present invention provides new bicyclic tetrahydroazepine derivatives having the general formula (I), wherein X, Y, R1, R2, R3, R4, R5, R6, R6a are as defined herein, compositions including the compounds, processes of manufacturing the compounds and methods of using them in the treatment of cancer. La présente invention concerne de nouveaux dérivés de tétrahydroazépine bicycliques de formule générale (I) dans laquelle X, Y, R1, R2, R3, R4, R5, R6, R6a sont tels que définis dans la description, des compositions comprenant les composés, des procédés de fabrication des composés et des procédés d'utilisation de ceux-ci dans le traitement du cancer.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER
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