BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER

The present invention provides new bicyclic tetrahydroazepine derivatives having the general formula (I), wherein X, Y, R1, R2, R3, R4, R5, R6, R6a are as defined herein, compositions including the compounds, processes of manufacturing the compounds and methods of using them in the treatment of canc...

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Bibliographische Detailangaben
Hauptverfasser:	BRITSCHGI, Adrian, KUEHNE, Holger, WICHMANN, Juergen, BRANDSTAETTER, Marco, LUEBBERS, Thomas, MUELLER, Barbara Johanna, HUTTER, Roman, KUHN, Bernd, MARTIN, Laetitia Janine
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides new bicyclic tetrahydroazepine derivatives having the general formula (I), wherein X, Y, R1, R2, R3, R4, R5, R6, R6a are as defined herein, compositions including the compounds, processes of manufacturing the compounds and methods of using them in the treatment of cancer. La présente invention concerne de nouveaux dérivés de tétrahydroazépine bicycliques de formule générale (I) dans laquelle X, Y, R1, R2, R3, R4, R5, R6, R6a sont tels que définis dans la description, des compositions comprenant les composés, des procédés de fabrication des composés et des procédés d'utilisation de ceux-ci dans le traitement du cancer.