3-ARYL-6-ARALKYL-1,4,5,6-TETRAHYDROPYRIDAZINE COMPOUND AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

A 3-aryl-6-aralkyl-1,4,5,6-tetrahydropyridazine compound, having the structure as shown in formula I. γ, δ-unsaturated N-aryl sulfonyl substituted hydrazone is subjected to a cyclization rearrangement reaction by means of a light and ruthenium complex catalysis method to prepare the 3-aryl-6-aralkyl...

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Hauptverfasser: LIU, Feng, AO, Guizhen, TU, Jialin
Format: Patent
Sprache:chi ; eng ; fre
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Zusammenfassung:A 3-aryl-6-aralkyl-1,4,5,6-tetrahydropyridazine compound, having the structure as shown in formula I. γ, δ-unsaturated N-aryl sulfonyl substituted hydrazone is subjected to a cyclization rearrangement reaction by means of a light and ruthenium complex catalysis method to prepare the 3-aryl-6-aralkyl-1,4,5,6-tetrahydropyridazine compound. The prepared 3-aryl-6-aralkyl-1,4,5,6-tetrahydropyridazine compound has a specific compound structure. The preparation method has the advantages of high yield, short synthetic route, environment-friendliness, simple post-treatment and wide substrate applicability, and effectively overcomes the defects in existing synthetic routes of large substrate limitation, troublesome post-treatment and the like. L'invention concerne un composé 3-aryl-6-aralkyle-1,4,5,6-tétrahydropyridazine, ayant la structure telle que représentée dans la formule I. De l'hydrazone substituée par N-aryle sulfonyle γ, δ-insaturé est soumise à une réaction de réarrangement par cyclisation au moyen d'un proc